Liphello tse Supileng tsa Antithrombotic li ile tsa sebelisoa

Tlhaloso e Khutšoanyane:

Ho na le mefuta e 'meli ea liprotheine mahlokong a noha, e 'ngoe ea eona e otlolohile.Ensaeme e qhaqhang fibrin (protolysin) e bitsoa fibrin (protolysin) enzyme (E khuts'oanyane bakeng sa plasminase,fi b ri no L yt I cenz YM E, FLE).Ntle le ho nyenyefatsa fibrin le fibrinogen, Ha ho ts'ebetso ea plasminogen 'meleng oa motho, ha ho na hydrolysis ea lintlha tse ling tsa coagulation Le lera la platelet, le na le phello e hlakileng ea antithrombotic.E 'ngoe ke ka khatello ea Prothrombin e kenngoa tšebetsong ho liehisa ts'ebetso ea coagulation mme ha e na ts'ebetso ea enzyme.

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Enzyme ena e ile ea hlahisoa ka lekhetlo la pele ke ATODA joalo-joalo ho tsoa ho mahloko a noha a hlooho ea tšepe ea Japane a botala bo bosehla
Ho ile ha buisanoa ka mokhoa oa anticoagulant oa protheine ea anticoagulant.
Sena se bontšoa ka ho sebelisana le clotting factor IX kapa clotting factor X ka li-ion tsa calcium
Sebopeho sa 1: 1 e rarahaneng ho finyella nako e telele ea coagulation;Hamorao,
LU et al.Agk ke strodona CU
ACFI, e leng anticoagulant factor, e ne e qheletsoe ka thoko ho chefo ea noha.Liu Qing
Liang et al.e ithutile ntho ea anticoagulant mme a fumana hore AC FI e na le ion ea calcium
'Me ts'ebetso ea eona ea anticoagulant le sebopeho sa sebaka se ne se amana le li-ion tsa calcium.
Ka mor'a moo, Xu Xiaolong et al.ho arola chefo ea agkistrodon halys ka mokhoa o ntlafalitsoeng oa karohano
Ntho e 'ngoe ea anticoagulant, ACFI I, le anticoagulant ea ntho ena ea anticoagulant.
Lipatlisiso tsa ts'ebetsong ea mochine, li fumane hore tse tšoanang le AC FI, ke mofuta oa bobeli.zhai
Ning le al.e arotse ntho e ncha ea anticoagulant ho tsoa ho chefo ea agkistrodon agkistrodon
Ho ile ha fumanoa hore ha ho na ts'ebetso ea fibrinolytic le phospholipase A
Ketso le ts'ebetso ea ho tsoa mali.Qian Xiaojiang et al ba tsoang Hunan ba hlahisitse lintlha tsa chefo ea agkistrodon
Likarolo tse sebetsang tsa Fibrinolytic li ile tsa aroloa 'me tsa tiisoa ke tlhahlobo ea thrombolytic in vitro
E na le phello e hlakileng ea thrombolytic.Bohloeki bo ne bo arotsoe ka mekhoa e meraro ea chromatographic
'Me mosebetsi oa enzyme o ile oa ntlafala haholo.Hobane karolo ea plasminase e na le
Karolo ea ho tsoa mali e thata ho aroloa 'me boleng ba eona ba kopo ea bongaka ha bo totobetse.Li Zhaoyan joalo-joalo.
Ka boiteko ba ho fumana enzyme ea fibrinolytic ntle le likarolo tsa mali, karabo ea kliniki ea enzyme ea fibrinolytic
Ka tšehetso ea tekheniki.Zhou Xianli [18] o ile a paka ka liteko hore
Ka bobeli thrombin le fibrinolytic enzyme ea agkistrodon halys venom li na le phello e hlakileng ea thrombolytic, empa
Tšusumetso e tobileng ea enzyme ea fibrinolytic e matla ho feta thrombin.
Kahoo thrombin ke thrombolytic butle-butle, ntlafatso e tsoelang pele ea methapo ea mali,
Ntlafatsa mamello ea methapo ea mali sebakeng sa ischemic, qoba ho tšeloa mali ho bakoang ke ho phatloha ha methapo ea mali.
Cleft, e na le phello e ntle sethaleng sa pele sa thrombosis, tse peli tse kopantsoeng li sebelisoa