Bohloko ba noha bo na le likarolo tse ngata tsa bioactive, haholo-holo ho kenyelletsa protease le polypeptide
E etsa karolo ea 90% ~ 95% ea boima bo omeletseng ba mahloko a noha [l
Ka tsoelo-pele e tsoelang pele ea theknoloji, liprotheine tse ngata tsa likokoana-hloko tse sebetsang ka chefo ea noha butle-butle
E 'nile ea aroloa' me ea hloekisoa, 'me batho ba entse joalo
Etsa liphuputso tse tebileng ka eona ka sepheo sa ho sebelisa metsoako ea meriana e chefo ea noha ho batho.
Phekolo ea mafu a tšoanang.Hona joale, metsoako e sebetsang ea lithethefatsi tse sebetsang tse nang le chefo ea noha
Patlisiso ea lithethefatsi le ts'ebeliso ea bongaka e etsoang li shebane haholo le antithrombotic, hemostatic le hypoglycemic
Khatello, anti-mofets'e le li-painkillers.
L Lithethefatsi tsa antithrombotic
Protease ea chefo ea noha e nang le litlamorao tsa anti-thrombotic le thrombolytic e kenyelletsa haholo Ancelor.
Enzyme (hoe crod), batmxobin, defibrase (de coerase) le Agkistrodon acutus
Enzyme (autobin).Tse tharo tsa pele ke tsa snaI [e venom
Thmmbin joalo ka li-enzynle, s Ⅷ.E), sVTLE ke serine protease, e tšoanang le
E na le ts'ebetso ea arginine esterase le amidase - 1. Enzyme e kang chefo ea noha ea thrombin
E sebetsa ho fibrinogen ho lokolla fibrinogen A kapa B, ka hona
E ka coagulate polymerization ea fibrin monomer hlooho le mohatla, hobane e bontša thrombin
E sebetsa 'me e bitsoa thrombin-like.Ka nako e ts'oanang, enzyme e kang chefo ea thrombin e ke ke ea fumanoa ho batho
E kenya tshebetsong coagulation factor x Ⅲ in vivo, mme fibrin monomer e hlahisoang ke hydrolysis ea eona e ka khona.
Hlooho le mohatla polymerization, empa e ke ke ea hlahisa lehlakoreng ketane cross-linking, eo ho leng bonolo ho senngoa ke tlhaho reticuloendothelial tsamaiso.
Boemo ba plasma fibrinogen bo fokotsehile ka lebaka la phagocytosis kapa ho senyeha ke tsamaiso ea fibrinolytic
E maemong a benign fibrinolytic, kahoo e bonts'a anticoagulation le khatello ea maikutlo 'meleng
Fibrillation H1.Agkistrodon acutus enzyme ke ea enzyme ea fibrinolytic, e leng fibrinolytic
Kgutsufatso ya enzyme [Erin (ogen) ol "icenzyme, FLE] e ka aroloa ka ketane e le 'ngoe.
Zinc metalloproteinase le single-chain kapa double-chain serine protease, haholo lehe la zinc metal
Enzyme e tšoeu.Enzyme ea fibrinolytic ea chefo ea noha ha e hloke activator, 'me e ka khaola likhoele ka kotloloho.
Protheine (protogen) e hlahisa hemofibrin, kahoo e ke ke ea baka ho kopana “J.
Ho tsoa mahlokong a Agkistrodon halys (mohlala, sek, № r [md ∞ ho, sekepe) ho la Malaysia
Ankylose e ka thōko e bile eona ea pele ea ho sebelisoa phekolong ea meriana ea mafu a thrombotic
SVTLE lithethefatsi.6 J. Kamora nts'etsopele ea Ancelose, e kile ea ithutoa ke linaha tse ngata
Bafuputsi ba lumela hore sV'11E ke moriana o tšepisang ka ho fetisisa oa ho phekola mafu a thrombotic,
Ntle le ho sebelisoa bakeng sa kalafo ea peripheral thrombosis, e ka sebelisoa hape bakeng sa kalafo ea thrombosis e tebileng ea venous le central venous thrombosis.
Pulse thrombosis e boetse e na le phello ea phekolo "J.Ka bo-1990, linaha le libaka tse ngata
Qu Du o thahasella haholo kalafo ea acute cerebral ischemia le stroke ka aclase, le
Morero oa lichelete: Morero oa Sesole sa Meriana ea Bongaka le Theknoloji ea Kholiso ea Bacha (13QNP068);Lebotho lohle “12
5 “porojeke e akaretsang ya dipatlisiso tsa bongaka (cwslJ280);Sebaka sa Sesole sa Chengdu "Leano la 12 la Lilemo Tse Hlano" Lipatlisiso tsa Bongaka
Merero ea bohlokoa (B12026);Morero o akaretsang oa lipatlisiso tsa bongaka oa Setereke sa Sesole sa Chengdu nakong ea Morero oa Lilemo tse Hlano oa 12
(C12062)
Sehlopha sa mongoli: 650032 Kunming, Setsi sa Setsi sa Sesole sa Chengdu sa Taolo le Thibelo ea Mafu (Zhang Zhixiao,
Hu Tingsong, Cui Qinghua, Zheng Ying, Fan Quanshui);Likokoana-hloko, Sekolo sa Meriana ea Motheo, Koleche ea Bongaka ea Youjiang bakeng sa Lichaba
Ofisi ea Thuto le Lipatlisiso ea Biology le Immunology (Xie Zhenfeng)
Mongoli ea ngollang: Fan Quanshui, E-mail: fqsl68@126 ．com
Ho entsoe lithuto tse 'maloa tse nyane tsa ts'ebeliso ea bongaka.Lethathamo la tlhahlobo ea tšebeliso ea lithethefatsi ea pele
Ntle le moo, Ancelose e ka sebelisoa kalafong ea bongaka ea bakuli ba nang le stroke se matla sa ischemic qalong
E bontša phello e ntle ea pholiso.Ka mor'a moo, ka palo e kholo ea randomized habeli-fofu, placebo para
Ho ea ka teko ea tleleniki, o ile a, joalo-joalo Bakeng sa 2613 linyeoe tsa a hlobaetsang le
Liphetho tsa kalafo ea lithethefatsi tsa bakuli ba nang le lefu la ischemic stroke li netefalitse hore bakuli ba sehlopha sa cloroxobin
Sekhahla sa ho pholoha se ile sa eketseha haholo, empa kotsi ea ho tsoa mali ka har'a cranial le eona e ile ea eketseha.Ka mor'a moo
Teko ea bongaka ea bakuli ba 1222 ba nang le lefu la ischemic stroke e netefalitse seo kamora lihora tse 3
Ancelose ha e khothalletsoe bakeng sa phekolo.1…. United States le Canada li phatlalalitsoe ka 2009
Liropo tse 500 tse amang linaha le libaka tse 12 ho kenyeletsoa Canada le Australia
hlokofatsoa ke
Nako ea poso: Feb-26-2023