Snake venom thrombin like enzyme (TLE) ke serine protease ea lelapa la trypsin, e nang le tatelano e bolokehileng haholoanyane le trypsin.E na le ts'ebetso ea arginine esterase, e ka nka khato ka ho toba ho fibrinogen, ea kenya letsoho ho phunyeha ha Arg2Gly peptide bond karolong e itseng ea molek'hule ea fibrinogen, e lokolla fibrinopeptide A (FPA) kapa B (FPB. Li-thrombin tse seng kae tsa alkaline li ile tsa aroloa ke kholomo ea phapanyetsano ea cation, e kopantsoe le gel filtration le affinity chromatography.Affinity chromatography e sebelisoa haholo ka lebaka la katleho ea eona e phahameng ea karohano le ho hlaphoheloa ha sampole.Ho sebelisoa mekhoa e fapaneng ea tlhoekiso,' me lihlahisoa tse fumanoeng le tsona li fapane. Guo Chunteng et al. [6, 7] ba fumane thrombin joalo ka likaroloana P3 le P4 ho tsoa mahlokong a Agkistrodon acutus Fujian ka ho sebelisa mekhoa e fapaneng ea tlhoekiso. mosebetsi wa ntho e kenyang tshebetsong
Nako ea poso: Dec-23-2022