[Abstract] Sepheo Ho fuputsa phello e thibelang ea karoloana e nyenyane ea molek'hule ea polypeptide (K karoloana) ho tloha ho Agkistrodon acutus venom mabapi le ho ata ha lisele tsa kankere ea mae a motho A2780 le mochine oa eona.Mekhoa ea tlhahlobo ea MTT e ne e sebelisetsoa ho lemoha thibelo ea kholo ea karolo ea K ho mela ea lisele tsa kankere;Tšusumetso ea anti-cell adhesion ea karolo ea K e ile ea bonoa ka tlhahlobo ea ho khomarela;AO-EB habeli fluorescence staining le flow cytometry li ile tsa sebelisoa ho bona ketsahalo ea apoptosis.Karolo ea Liphetho ea K e thibetse ho ata ha lisele tsa kankere ea mahe a batho A2780 kamanong ea nako le phello ea lethal dose, 'me e ka hanela ho khomarela ha lisele ho FN.Apoptosis e ile ea fumanoa ke AO-EB double fluorescence staining le flow cytometry.Qetello Karolo ea K e na le phello e kholo ea ho thibela ho ata ha lisele tsa kankere ea mahe a batho A2780 in vitro, 'me mochine oa eona o ka amana le ho thibela lisele le ho kenngoa ha apoptosis.
Nako ea poso: Jan-11-2023